Thyroglobulin (F5O9B) Rabbit mAb #57387
- WB
- IHC
Supporting Data
| REACTIVITY | H |
| SENSITIVITY | Endogenous |
| MW (kDa) | 300 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IHC-Immunohistochemistry
Species Cross-Reactivity Key:
- H-Human
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
| Immunohistochemistry (Paraffin) | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
Thyroglobulin can be used as a tumor marker for certain types of thyroid cancer, particularly papillary and follicular thyroid cancer. These cancers produce thyroglobulin, so elevated levels of thyroglobulin in the blood can indicate the presence of cancer. Thyroglobulin levels can also be used to monitor the effectiveness of thyroid cancer treatment (2). In addition to its role in thyroid cancer, thyroglobulin can also be involved in autoimmune thyroid diseases, such as Hashimoto's thyroiditis and Graves' disease. In these conditions, the body's immune system attacks thyroglobulin, leading to inflammation and damage to the thyroid gland (2).
Limited Uses
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