Phospho-GRB2 (Tyr160) (F3B5U) Rabbit mAb #70904
- WB
Product Specifications
| REACTIVITY | H M |
| SENSITIVITY | Endogenous |
| MW (kDa) | 25 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
Product Information
Product Usage Information
| Application | Dilution |
|---|---|
| Western Blotting | 1:1000 |
Storage
Protocol
Specificity / Sensitivity
Species Reactivity:
Source / Purification
Background
GRB2 is phosphorylated at Tyr160 by NPM-ALK kinase and Src kinase (3,4). The phosphorylation promotes its disassociation from dimer to monomer, stabilizes its association with SOS, and activates the downstream MAP kinase signaling (5).
Limited Uses
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