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  2. Primary Antibodies /
  3. p90RSK Antibody Sampler Kit

p90RSK Antibody Sampler Kit #9326

    Product Information

    Kit Usage Information

    Protocols

    Product Description

    The p90RSK Antibody Sampler Kit provides an economical means of evaluating levels of p90RSK protein phosphorylated at specific sites, as well as total p90RSK protein levels. The kit contains enough primary and secondary antibody to perform two Western blot experiments.

    Background

    The 90 kDa ribosomal S6 kinases (RSK1-4) are a family of widely expressed Ser/Thr kinases characterized by two nonidentical, functional kinase domains (1) and a carboxy-terminal docking site for extracellular signal-regulated kinases (ERKs) (2). Several sites both within and outside of the RSK kinase domain, including Ser380, Thr359, Ser363, and Thr573, are important for kinase activation (3). RSK1-3 are activated via coordinated phosphorylation by MAPKs, autophosphorylation, and phosphoinositide-3-OH kinase (PI3K) in response to many growth factors, polypeptide hormones, and neurotransmitters (3).

    Database Links

    UniProt ID: P51812 , Q15349 , Q15418


    Entrez-Gene Id: 6197 , 6196 , 6195


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    For Research Use Only. Not For Use In Diagnostic Procedures.
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