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Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.

BASP1 (F9A5E) Rabbit mAb #96510

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  • WB
  • IHC
  • IF

    Supporting Data

    REACTIVITY H
    SENSITIVITY Endogenous
    MW (kDa) 70
    Source/Isotype Rabbit IgG
    Application Key:
    • WB-Western Blotting 
    • IHC-Immunohistochemistry 
    • IF-Immunofluorescence 
    Species Cross-Reactivity Key:
    • H-Human 

    Product Information

    Product Usage Information

    Application Dilution
    Western Blotting 1:1000
    Immunohistochemistry (Paraffin) 1:1600 - 1:6400
    Immunofluorescence (Immunocytochemistry) 1:1600

    Storage

    Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol, and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.

    Protocol

    Specificity / Sensitivity

    BASP1 (F9A5E) Rabbit mAb recognizes endogenous levels of total BASP1 protein. Non-specific staining was observed in cardiac and skeletal muscle by immunohistochemistry.

    Species Reactivity:

    Human

    Source / Purification

    Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human BASP1 protein.

    Background

    Brain acid soluble protein 1 (BASP1) was originally isolated from brain extracts. It is abundant in nerve terminals during brain development and is implicated in neurite outgrowth, maturation of the actin cytoskeleton, organization of the plasma, and axon regeneration (1-3). Actin dynamics regulation and presynaptic vesicle cycling at axon terminals by BASP1 facilitate axon regeneration (2). Furthermore, the BASP1 gene is downregulated in many human tumor cell lines, particularly in those derived from leukemias (4).
    For Research Use Only. Not for Use in Diagnostic Procedures.
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